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الأبحاث & المؤلفات المنشورة

إن البحث العلمي والطبي في مجال البيولوجيا الجزيئية والطبية بشكل عام، وأبحاث الجينات السرطانية والخلايا الجذعية البشرية بشكل خاص، ونشره نشراً علمياً محكماً وموثوقاً سوف يعود بالفائدة والنفع الكبير على الباحثين، المجتمع المحلي والعالمي، بالإضافة إلى الإنسانية، وخاصةً إذا كان البحث مسخر لخدمة البشر وتحسين صحتهم من خلال الاكتشافات والابتكارات العلمية الجديدة. الاستفادة من الأبحاث العلمية ونشرها تشمل التدريب المستمر للباحثين على تقنيات ومهارات المختبر الطبي والجزيئي، التي تجعلهم قادرين على الإبداع في العمل المختبري الذي سوف يساهم ويساعد في اكتشاف كل جديد ونشره لمساعدة المرضى وعلاج الأمراض.


 Kumar, I.P., Priya, P.S., Meenatchi, R., Oyouni, A.A.A., Al-Amer, O.M., Aljohani, S.A.S., Pashameah, R.A., Hamadi, A., Alanazi, M.A. and Arockiaraj, J., 2022. Potential mechanism of Jatropha gossypifolia phenolic derivatives in enhancing insulin-signalling cascades GLUT 4, IRβ and GSK-3β in streptozotocin nicotinamide induced type II diabetic in wistar rat model. Journal of King Saud University-Science, p.102223.

 Hijazy, H.H.A., Dahran, N., Althagafi, H.A., Alharthi, F., Habotta, O.A., Oyouni, A.A.A., Algahtani, M., Theyab, A., Al-Amer, O., Lokman, M.S. and Alsharif, K.F., 2022. Thymoquinone counteracts oxidative and inflammatory machinery in carrageenan-induced murine paw edema model.

 Seshadri, V.D., Oyouni, A.A.A., Bawazir, W.M., Alsagaby, S.A., Alsharif, K.F., Albrakati, A. and Al‐Amer, O.M., 2022. Zingiberene exerts chemopreventive activity against 7, 12‐dimethylbenz (a) anthracene‐induced breast cancer in Sprague‐Dawley rats. Journal of Biochemical and Molecular Toxicology, p.e23146.

 Hawsawi, Y.M., Shams, A., Theyab, A., Abdali, W.A., Hussien, N.A., Alatwi, H.E., Alzahrani, O.R., Oyouni, A.A.A., Babalghith, A.O. and Alreshidi, M., 2022. BARD1 mystery: tumor suppressors are cancer susceptibility genes. BMC cancer, 22(1), pp.1-23.

 Seshadri, V.D., Oyouni, A.A.A., Hawsawi, Y.M., Aljohani, S.A.S., Al-Amer, O.M., AlZamzami, W. and Mufti, A.H., 2022. Chemopreventive role of Tin oxide-Chitosan-Polyethylene glycol-Crocin nanocomposites against Lung cancer: An in vitro and in vivo approach. Process Biochemistry, 120, pp.186-194.

 Alatawi, K.K.Z., Albalawi, K.S.D., Aljuhani, A.A.M., Albalawi, N.S.D., Alalawy, A.I. and Oyouni, A.A.A., 2022. Drug detection tests and the important factors and effects of the development of addiction. Journal of King Saud University-Science, p.102093.

 Hussein, M.M., Althagafi, H.A., Alharthi, F., Albrakati, A., Alsharif, K.F., Theyab, A., Kassab, R.B., Mufti, A.H., Algahtani, M., Oyouni, A.A.A. and Baty, R.S., 2022. Apigenin attenuates molecular, biochemical, and histopathological changes associated with renal impairments induced by gentamicin exposure in rats. Environmental Science and Pollution Research, pp.1-13.

 Barnawi, I., Hawsawi, Y.M., Dash, P., Oyouni, A.A.A., Mustafa, S.K., Hussien, N.A., Al-Amer, O., Alomar, S. and Mansour, L., 2022. Nitric Oxide Synthase potentiates the resistance of cancer cell lines to anticancer chemotherapeutics. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents), 22(7), pp.1397-1406.

 Cai, Y., Karmakar, B., AlSalem, H.S., El-kott, A.F., Bani-Fwaz, M.Z., Negm, S., Oyouni, A.A.A., Al-Amer, O. and Batiha, G.E.S., 2022. Oak gum mediated green synthesis of silver nanoparticles under ultrasonic conditions: Characterization and evaluation of its antioxidant and anti-lung cancer effects. Arabian Journal of Chemistry, 15(6), p.103848. 

 Kassab, R.B., Elbaz, M., Oyouni, A.A., Mufti, A.H., Theyab, A., Al-Brakati, A., Mohamed, H.A., Hebishy, A., Elmallah, M.I., Abdelfattah, M.S. and Abdel Moneim, A.E., 2022. Anticolitic activity of prodigiosin loaded with selenium nanoparticles on acetic acid–induced colitis in rats. Environmental Science and Pollution Research, pp.1-13.

 Oyouni, A.A.A., 2022. Biological and genetic basis of various human genetic disorders and the application of biological and genetic markers. Journal of King Saud University-Science, p.101961.

 Cai, Y., Karmakar, B., Salem, M.A., Alzahrani, A.Y., Bani-Fwaz, M.Z., Oyouni, A.A.A., Al-Amer, O. and Batiha, G.E.S., 2022. Ag NPs supported chitosan-agarose modified Fe3O4 nanocomposite catalyzed synthesis of indazolo [2, 1-b] phthalazines and anticancer studies against liver and lung cancer cells. International Journal of Biological Macromolecules, 208, pp.20-28.

 Wang, C., Karmakar, B., Awwad, N.S., Ibrahium, H.A., El-kott, A.F., Abdel-Daim, M.M., Oyouni, A.A.A., Al-Amer, O. and Batiha, G.E.S., 2022. Bio-supported of Cu nanoparticles on the surface of Fe3O4 magnetic nanoparticles mediated by Hibiscus sabdariffa extract: Evaluation of its catalytic activity for synthesis of pyrano [3, 2-c] chromenes and study of its anti-colon cancer properties. Arabian Journal of Chemistry, 15(6), p.103809.

 Lokman, M. S., Zaafar, D., Althagafi, H. A., Abdel Daim, M. M., Theyab, A., Hasan Mufti, A., Algahtani, M., Habotta, O. A., Alghamdi, A. A. A., Alsharif, K. F., Albrakati, A., Oyouni, A. A. A., Bauomy, A. A., Baty, R. S., Zhery, A. S., Hassan, K. E., Abdel Moneim, A. E., & Kassab, R. B. (2022). Antiulcer activity of proanthocyanidins is mediated via suppression of oxidative, inflammatory, and apoptotic machineries. Journal of Food Biochemistry, 46, e14070. https://doi.org/10.1111/jfbc.14070

 Al-Amer, O.M., Oyouni, A.A.A., Alshehri, M.A., Alasmari, A., Alzahrani, O.R., Aljohani, S.A.S., Alasmael, N., Theyab, A., Algahtani, M., Al Sadoun, H. and Alsharif, K.F., 2021. Association of SNPs within TMPRSS6 and BMP2 genes with iron deficiency status in Saudi Arabia. PloS one, 16(11), p.e0257895


 Sarkar, P., Guru, A., Raju, S.V., Farasani, A., Oyouni, A.A.A., Alzahrani, O.R., Althagafi, H.A.E., Alharthi, F., Karuppiah, K.M. and Arockiaraj, J., 2021. GP13, an Arthrospira platensis cysteine desulfurase-derived peptide, suppresses oxidative stress and reduces apoptosis in human leucocytes and zebrafish (Danio rerio) embryo via attenuated caspase-3 expression. Journal of King Saud University-Science, 33(8), p.101665.


 Adiga, U., Adiga, S., Nandit, P.B., Manjeera, L., Rao, A., Ghilan, A.K.M., Oyouni, A.A.A., Hawsawi, Y.M., Theyab, A., Algahtani, M. and Alzahrani, O.R., 2022. A cross-sectional study on the association of single nucleotide polymorphism of leptin receptor (Gln223Arg) and insulin resistance in gestational diabetes mellitus. Journal of King Saud University-Science, 34(1), p.101662


 Alanazi, I.O., Shaik, J.P., Parine, N.R., Azzam, N.A., Alharbi, O., Hawsawi, Y.M., Oyouni, A.A.A., Al-Amer, O.M., Alzahrani, F., Almadi, M.A. and Aljebreen, A.M., 2021. Association of HER1 and HER2 gene variants in the predisposition of colorectal Cancer. Journal of Oncology, 2021


 El-Magd, M.A., Abdelfattah-Hassan, A., Elsisy, R.A., Hawsawi, Y.M., Oyouni, A.A., Al-Amer, O.M. and El-Shetry, E.S., 2021. Expression and function of Ebf1 gene during chondrogenesis in chick embryo limb buds. Gene, 803, p.145895.


 Al-Brakati, A., Alsharif, K.F., Alzahrani, K.J., Kabrah, S., Al-Amer, O., Oyouni, A.A., Habotta, O.A., Lokman, M.S., Bauomy, A.A., Kassab, R.B. and Moneim, A.E.A., 2021. Using green biosynthesized lycopene-coated selenium nanoparticles to rescue renal damage in glycerol-induced acute kidney injury in rats. International Journal of Nanomedicine, 16, p.4335.


 Zedan, A.M., Sakran, M.I., Bahattab, O., Hawsawi, Y.M., Al-Amer, O., Oyouni, A.A., Nasr Eldeen, S.K. and El-Magd, M.A., 2021. Oriental hornet (Vespa orientalis) larval extracts induce antiproliferative, antioxidant, anti-inflammatory, and anti-migratory effects on mcf7 cells. Molecules, 26(11), p.3303.

Khalid M. S, Aljohani M. H. M, Alomrani A. N, Oyouni A. A, Alzahrani O, Ahmad M. A, Al-Aoh A. H, Ajmal M. R, Sarıkavaklı N, Mohammedsaleh M. Z, Shater F. A. COVID-19 and Immune Function – “A Significant” Zinc. Orient J Chem 2020;36(6).

Hawsawi, Y.M., Zailaie, S.A., Oyouni, A.A.A. et al. Prostate cancer and therapeutic challenges. J of Biol Res-Thessaloniki 27, 20 (2020). https://doi.org/10.1186/s40709-020-00128-z.

Oyouni, A.A.A., Mustafa, S.K., Alzahrani, O., Al-Amer, O., Al-Harbi, A.R. and Saggu, S., 2020. End Stage Renal Disease (ESRD) Incidence Rates in Saudi Arabia: Current Scenario in Tabuk region. Bioscience Research.

Mustafa, S.K., Ahmad, M.A., Baranova, V., Deineko, Z., Lyashenko, V. and Oyouni, A.A.A., 2020. Using Wavelet Analysis to Assess the Impact of COVID-19 on Changes in the Price of Basic Energy Resources.

PAVLOVA, V., POPOV, B.B., HRISTOVA, V.K., MUSTAFA, S.K., OYOUNI, A.A.A., AJMAL, M.R., AHMAD, M.A., ALZAHRANI, O., ELSAYED, A.A. and SHARIATI, M.A., 2020. Chemical characterization of VARUMIN (1 and 2) oral solutions as potential therapeutic beverages. International Journal of Pharmaceutical Research, 12(2).

Al-Amer, O., Hawasawi, Y., Oyouni, A.A.A., Alshehri, M., Alasmari, A., Alzahrani, O. and Aljohani, S.A.S., 2020. Study the association of Transmembrane Serine Protease 6 Gene Polymorphisms with Iron Deficiency Status in Saudi Arabia. Gene, p.144767.

Mustafa, S.K., Oyouni, A.A.W.A., Aljohani, M.M. and Ahmad, M.A., 2020. Polyphenols more than an Antioxidant: Role and Scope. J. Pure Appl. Microbiol, 14(1), pp.47-61.

 Oyouni, A.A.A., AlHarbi, A.R., Mustafa, S.K., ShahzadAslam, M. and Ahmad, M.A., 2020. Some Aspects of Radiation Safety due to Electromagnetic Field in Normal Human Life. Current Trends in Biotechnology & Pharmacy.

Saggu, S., Rehman, H., Alzeibr, F.M., Oyouni, A.A.A., Zidan, N., Panneerselvam, C. and Trivedi, S., 2019. Cymbopogon schoenanthus (Ethkher) ameliorates cadmium induced toxicity in swiss albino mice. Saudi journal of biological sciences, 26 (7), pp.1875-1881.

Saggu, S., Oyouni, A.A.A., Rehman, H. and Farasani, A., Addiction Of Chewing Tobacco, Shamma And Khat: Pervasiveness Of Oral Cancer In Saudi Arabia ., Indo Am. J. P. Sci, 2019; 06 (05).

 Oyouni, A.A.A., Saggu, S., Tousson, E., Mohan, A. and Farasani, A., 2019. Mitochondrial nephrotoxicity induced by tacrolimus (FK-506) and modulatory effects of Bacopa monnieri (Farafakh) of Tabuk Region. Pharmacognosy Research, 11(1), p.20.

Hawsawi, Y.M., Al‐Numair, N.S., Sobahy, T.M., Al‐Ajmi, A.M., Al‐Harbi, R.M., Baghdadi, M.A., Oyouni, A.A. and Alamer, O.M., 2019. The role of BRCA1/2 in hereditary and familial breast and ovarian cancers. Molecular genetics & genomic medicine, p.e879.

Hawsawi, Y.M., Al-Zahrani, F., Mavromatis, C., Baghdadi, M.A., Saggu, S. and Oyouni, A.A.A., 2018. Stem cell applications for treatment of cancer and autoimmune diseases: its promises, obstacles, and future perspectives. Technology in cancer research & treatment, 17, p.1533033818806910.

Al-Amer, O., Oyouni, A.A.A., Alshehri, M. and Alzaheb, R.A., 2018. Transferrin (re3811647) gene polymorphism in iron deficiency anemia in Saudi Arabia. Prof. RK Sharma, 12 (3).

 Oyouni, A.A.A., Saggu, S., Tousson, E. and Rehman, H., 2018. Immunosuppressant drug tacrolimus induced mitochondrial nephrotoxicity, modified PCNA and Bcl-2 expression attenuated by Ocimum basilicum L. in CD1 mice.

Toxicology Reports. Al-Amer, O., Oyouni, A.A.A. and Saggu, S., 2017. Molecular Targeted Therapy for Breast Cancer: A New Frontiers. Biosciences Biotechnology Research Asia, 14 (3), pp.953-959.

Oyouni, A.A.A., 2017. Human Cancer Genetics, Stem Cells, and Medical Molecular Biology: An Epigrammatic Review. Biosciences Biotechnology Research Asia, 14 (3), pp.881-885.

Oyuoni, A.A.A., Rehman, H. and Saggu, S., 2017. Addiction of tobacco, Shamma and Khat: Incidence of oral cancer in Saudi Arabia. Toxicology Letters, 280, p.S89.

Oyuoni, A.A.A., Saggu, S., Rehman, H., Toussan, E. and Al Thabiani, A., 2017. Suppression of FK506 induced nephrotoxicity in mice by Bacopa monnierii. Toxicology Letters, 280, p.S139.

Rehman, H., Saggu, S., Oyuoni, A.A.A. and Al Thibiani, A., 2017. Modulatory role of Ociumum basilicum (Al-Rehan) leaves against 4-tert-octyl phenol induced oxidative stress in rats. Toxicology Letters, 280, p.S136.

Saggu, S., Rehman, H. and Oyouni, A.A.A., 2017. Pervasiveness of breast cancer in Saudi Arabia. Toxicology Letters, 280, p.S247.

Saggu, S., Rehman, H., Alzeibr, F.M., Oyouni, A.A.A., Zidan, N., Panneerselvam, C. and Trivedi, S., 2017. Cymbopogon schoenanthus (Ethkher) ameliorates cadmium induced toxicity in swiss albino mice. Saudi Journal of Biological Sciences.

Oyouni, A.A.A., 2016. The medical biomarker and oncogenic potential of the human cancer-and stem/germ cell-specific gene TDRD12 (Doctoral dissertation, Prifysgol Bangor University).

         

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